Query: NC_009718:1207360 Fervidobacterium nodosum Rt17-B1, complete genome Lineage: Fervidobacterium nodosum; Fervidobacterium; Thermotogaceae; Thermotogales; Thermotogae; Bacteria General Information: Fervidobacterium nodosum is a thermophilic, Gram-negative, motile, non-sporulating, glycolytic, obligately anaerobic rod that exists singly, in pairs or in chains. Fervidobacterium nodosum was isolated from a hot spring in New Zealand. Its optimal growth temperature is 65 to 70 degrees Celsius. The cellular morphology of this organism, a member of the Thermotogales, is characterized by a terminal spherical extension of the cell envelope.
- Sequence; - BLASTP hit: hover for score (Low score = Light, High score = Dark); - hypothetical protein; - cds: hover for description
General Information: Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.