Query: NC_009714:1576401 Campylobacter hominis ATCC BAA-381, complete genome Lineage: Campylobacter hominis; Campylobacter; Campylobacteraceae; Campylobacterales; Proteobacteria; Bacteria General Information: Campylobacter hominis ATCC BAA-381 was isolated from the feces of a healthy human. Members of this genus are one of the most common causes of bacterial gastroenteritis (campylobacteriosis). Usually the symptoms are abdominal pain, fever, diarrhea, and cramps, but the illness can sometimes be fatal and some infected individuals develop a syndrome (Guillain-Barre) in which the nerves connecting the spinal cord to the brain are damaged. C. jejuni is the main cause of campylobacteriosis, but other species can also cause infection, including C. coli, C. upsaliensis, and C. concisus. Campylobacter hominis. This is the only known species of Campylobacter that is not pathogenic to humans.
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General Information: This strain is an egg-passaged attentuated avirulent strain that has been used as a live vaccine and was originally isolated from a typhus patient in Madrid. This species is the causal agent of typhus. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host.