Query: NC_009707:36024 Campylobacter jejuni subsp. doylei 269.97 chromosome, complete Lineage: Campylobacter jejuni; Campylobacter; Campylobacteraceae; Campylobacterales; Proteobacteria; Bacteria General Information: Isolated from a blood sample of human bacteremia in South Africa. Causes food poisoning. This organism is the leading cause of bacterial food poisoning (campylobacteriosis) in the world, and is more prevalent than Salmonella enteritis (salmonellosis). Found throughout nature, it can colonize the intestines of both mammals and birds, and transmission to humans occurs via contaminated food products. This organism can invade the epithelial layer by first attaching to epithelial cells, then penetrating through them. Systemic infections can also occur causing more severe illnesses
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General Information: Salmonella enterica subsp. enterica serovar Agona causes gastroenteritis in humans and is also pathogenic to swine and other food animals. This serovar is able to contain the Salmonella genomic island 1 multidrug resistance gene cluster. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.