Pre_GI: SWBIT SVG BLASTP

Query: NC_009706:830461 Clostridium kluyveri DSM 555 chromosome, complete genome

Lineage: Clostridium kluyveri; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Involved in production of caproic acid in co-culture with a methanogen. This species was enriched from mud in a co-culture with Methanobacterium omelianskii. When grown on ethanol C. kluyveri produce caproic acid in addition to acetic acid. This organism is able to grow anaerobically on ethanol and acetate as sole energy sources.

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BLASTP Alignment.txt

Subject: NC_008011:1394777 Lawsonia intracellularis PHE/MN1-00, complete genome

Lineage: Lawsonia intracellularis; Lawsonia; Desulfovibrionaceae; Desulfovibrionales; Proteobacteria; Bacteria

General Information: Lawsonia intracellularis PHE/MN1-00 was isolated from intestinal mucosal lesions in pigs that had proliferative enteropathy (PE). When introduced into health pigs, this organism produced the clinical and histological signs of PE. Causative agent for proliferative enteropathy in swine. This organism causes proliferative enteropathy (ileitis) in swine and other domesticated animals resulting in severe losses each year. This obligate intracellular pathogen infects the mucosa of the lower intestinal tract by initially infecting crypt cells, which are precursors that normally grow and divide in order to replace the epithelial cells. Once infection occurs, the crypt cells are stimulated to grow and divide abnormally, resulting in the proliferative phenotype. In severe cases of the disease the entire bowel can become affected and persist for up to 40 days, greatly affecting the host animal.