Query: NC_009674:2551759 Bacillus cytotoxicus NVH 391-98 chromosome, complete genome Lineage: Bacillus cytotoxicus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria General Information: Isolated from a food poisoning outbreak in a nursing home for elderly people in France in March 1998. Under starvation conditions this group of bacteria initiate a pathway that leads to endospore formation, a process that is thoroughly studied and is a model system for prokaryotic development and differentiation. Spores are highly resistant to heat, cold, dessication, radiation, and disinfectants, and enable the organism to persist in otherwise inhospitable environments. Under more inviting conditions the spores germinate to produce vegetative cells. Bacillus cytotoxicus is a member of the Bacillus cereus group, which represents sporulating soil bacteria containing pathogenic strains which may cause food poisoning outbreaks.
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General Information: This strain is a methicillin-resistant (MRSA) strain isolated in 1982 from a pharyngeal smear of a Japanese patient. Causes skin infections. Staphylcocci are generally found inhabiting the skin and mucous membranes of mammals and birds. Some members of this genus can be found as human commensals and these are generally believed to have the greatest pathogenic potential in opportunistic infections. This organism is a major cause of nosocomial (hospital-acquired) and community-acquired infections. S. aureus continues to be a major cause of mortality and is responsible for a variety of infections including, boils, furuncles, styes, impetigo and other superficial skin infections in humans. Also known to cause more serious infections particularly in the chronically ill or immunocompromised. The ability to cause invasive disease is associated with persistance in the nasal cavity of a host.