Pre_GI: SWBIT SVG BLASTP

Query: NC_009664:1569335 Kineococcus radiotolerans SRS30216, complete genome

Lineage: Kineococcus radiotolerans; Kineococcus; Kineosporiaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This organism is a coccoid bacterium originally isolated from a high-level radioactive waste cell at the Savannah River Site in Aiken, South Carolina, USA, in 2002. Radiation-resistant bacterium. Similarly to Deinococcus radiodurans, K. radiotolerans exhibits a high degree of resistance to ionizing gamma-radiation. Cells are also highly resistant to dessication. Kineococcus-like 16S rRNA gene sequences have been reported from the Mojave desert and other arid environments where these bacteria seem to be ubiquitous. Because of its high resistance to ionizing radiation and desiccation, K. radiotolerans has potential use in applications involving in situ biodegradation of problematic organic contaminants from highly radioactive environments. Moreover, comparative functional genomic characterization of this species and other known radiotolerant bacteria such as Deinococcus radiodurans and Rubrobacter xylanophilus will shed light onto the strategies these bacteria use for survival in high radiation environments, as well as the evolutionary origins of radioresistance and their highly efficient DNA repair machinery. This organism produces an orange carotenoid-like pigment. Cell growth occurs between 11-41 degresss C, pH 5-9, and in the presence of <5% NaCl and <20% glucose. Carbohydrates and alcohols are primary growth substrates.

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BLASTP Alignment.txt

Subject: NC_008148:1567703 Rubrobacter xylanophilus DSM 9941, complete genome

Lineage: Rubrobacter xylanophilus; Rubrobacter; Rubrobacteraceae; Rubrobacterales; Actinobacteria; Bacteria

General Information: Cellulose-degrading bacterium. This genus contains two species: Rubrobacter radiotolerans and Rubrobacter xylanophilus. These two species represent the oldest lineage (deepest branch) of the Actinobacteria and are distantly related to Mycobacteria and Streptomycetes. Both species are thermophilic and exhibit high tolerance to radiation. Very little research has been done on these organisms and little is known other than their taxonomic characterization. Rubrobacter xylanophilus was isolated from a thermally polluted industrial runoff in the United Kingdom. Some strains of this species are capable of degrading hemicellulose and xylan (polymers of plant origin), and could play a significant role in the degradation of these compounds in the wood and paper industry as well as in the environment.