Pre_GI: SWBIT SVG BLASTP

Query: NC_009656:4527457 Pseudomonas aeruginosa PA7 chromosome, complete genome

Lineage: Pseudomonas aeruginosa; Pseudomonas; Pseudomonadaceae; Pseudomonadales; Proteobacteria; Bacteria

General Information: Non-respiratory clinical isolate from Argentina. Opportunistic pathogen. Bacteria belonging to the Pseudomonas group are common inhabitants of soil and water and can also be found on the surfaces of plants and animals. Pseudomonas bacteria are found in nature in a biofilm or in planktonic form. Pseudomonas bacteria are renowned for their metabolic versatility as they can grow under a variety of growth conditions and do not need any organic growth factors. This organism is an opportunistic human pathogen. While it rarely infects healthy individuals, immunocompromised patients, like burn victims, AIDS-, cancer- or cystic fibrosis-patients are at increased risk for infection with this environmentally versatile bacteria. It is an important soil bacterium with a complex metabolism capable of degrading polycyclic aromatic hydrocarbons, and producing interesting, biologically active secondary metabolites including quinolones, rhamnolipids, lectins, hydrogen cyanide, and phenazines. Production of these products is likely controlled by complex regulatory networks making Pseudomonas aeruginosa adaptable both to free-living and pathogenic lifestyles. The bacterium is naturally resistant to many antibiotics and disinfectants, which makes it a difficult pathogen to treat.

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Subject: NC_009138:1974935 Herminiimonas arsenicoxydans, complete genome

Lineage: Herminiimonas arsenicoxydans; Herminiimonas; Oxalobacteraceae; Burkholderiales; Proteobacteria; Bacteria

General Information: Herminiimonas arsenicoxydans was isolated from heavy metal contaminated sludge from an industrial water treatment plant. This organism has a number of mechanisms for metabolizing arsenic allowing it to effectively colonize arsenic-contaminated environments. A bacterium capable of oxidizing and reducing arsenic. This heterotrophic bacterium is capable of reducing and oxidizing arsenic with the objective of detoxification. Arsenic is both a product from natural sources and of human activities, and is widely distributed in the environment, essentially in 3 different oxidation states: As (-III) (arsine), As (+III) (arsenite) and As (+V) (arseniate). The ecology of this metalloid is strongly dependent on microbial transformations which affect the mobility and bioavailability as well as the toxicity of arsenic in the environment.