Pre_GI: SWBIT SVG BLASTP

Query: NC_009655:866281 Actinobacillus succinogenes 130Z chromosome, complete genome

Lineage: Actinobacillus succinogenes; Actinobacillus; Pasteurellaceae; Pasteurellales; Proteobacteria; Bacteria

General Information: Succinate-producing bacterium. Originally isolated from bovine rumen, this species is one of the most promising succinate producers known. It can utilize a variety of sugars and produce a very high volume of succinate, which is used by the pharmaceutical industry. This organism has been improved over time by growth on fermentable carbon and sodium monofluoroacetate and selection of fluoroacetate-resistant mutants which have a higher succinate yield. The succinate yield has also been improved via a metabolic engineering approach, by cloning and overproducing the PEP-carboxykinase gene which catalyzes the addition of carbon dioxide to PEP to form oxalacetate and can work physiologically in both directions

Subject: NC_012778:137064 Eubacterium eligens ATCC 27750, complete genome

Lineage: Eubacterium eligens; Eubacterium; Eubacteriaceae; Clostridiales; Firmicutes; Bacteria

General Information: Eubacterium eligens ATCC 27750 is part of the normal human gut flora. This genus has been isolated as normal flora from feces, rumen, and periodontal tissue. Eubacterium spp. are thought to play a beneficial role in maintaining the normal ecology of the large intestine, in part by producing chemicals like butyric acid which act to inhibit the growth of other bacteria. These organisms are occasionally isolated from wounds and abscesses and may be an opportunistic pathogen. This genus has also been isolated from sewage and soil.