Query: NC_009632:2257764 Staphylococcus aureus subsp. aureus JH1 chromosome, complete Lineage: Staphylococcus aureus; Staphylococcus; Staphylococcaceae; Bacillales; Firmicutes; Bacteria General Information: A series of isogenic methicillin-resistant (MRSA) strains were isolated from a patient undergoing vancomycin treatment. Causes skin infections. Staphylcocci are generally found inhabiting the skin and mucous membranes of mammals and birds. Some members of this genus can be found as human commensals and these are generally believed to have the greatest pathogenic potential in opportunistic infections. This organism is a major cause of nosocomial (hospital-acquired) and community-acquired infections. S. aureus continues to be a major cause of mortality and is responsible for a variety of infections including, boils, furuncles, styes, impetigo and other superficial skin infections in humans. Also known to cause more serious infections particularly in the chronically ill or immunocompromised. The ability to cause invasive disease is associated with persistance in the nasal cavity of a host.
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General Information: Rickettsia massiliae MTU5 was isolated from the tick Rhipicephalus turanicus collected from horses in Le Sambuc, Bouches-du Rhone, France. Members of this genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens. In both groups, the bacteria are transmitted via an insect, usually a tick, to a host organism where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Rickettsia massiliae is a member of the spotted fever group of the Rickettsiales and has been isolated from ticks in Europe and Africa. Rickettsia massiliae does not appear to cause disease in humans.