Pre_GI: SWBIT SVG BLASTP

Query: NC_009613:1337536 Flavobacterium psychrophilum JIP02/86, complete genome

Lineage: Flavobacterium psychrophilum; Flavobacterium; Flavobacteriaceae; Flavobacteriales; Bacteroidetes; Bacteria

General Information: Flavobacterium psychrophilum JIP02/86 (ATCC 49511) is a virulent strain. Flavobacterium psychrophilum cause cold water disease in salmon and trout. This bacterium causes septicemia in young fish (rainbow trout fry syndrome) and extensive lesions in adult fish. There is a high rate of mortality associated with these diseases with considerable economic impact for the aquaculture industry.

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Subject: NC_006570:141966 Francisella tularensis subsp. tularensis Schu 4, complete genome

Lineage: Francisella tularensis; Francisella; Francisellaceae; Thiotrichales; Proteobacteria; Bacteria

General Information: This subspecies is virulent in humans, and the strain is a clinical isolate that is also virulent in an animal model. Originally isolated from a human case of tularemia in 1951. There are a large number of insertion sequences including a mariner element, which is a transposon typically found in eukaryotes and is the first instance of this element to be found in a microbe, which may have acquired it during transit through one of the insect vectors. Causative agent of tularemia. This organism was first identified by Edward Francis as the causative agent of a plague-like illness that affected squirrels in Tulare county in California in the early part of the 20th century. The organism now bears his name. The disease, which has been noted throughout recorded history, can be transmitted to humans by infected ticks or deerflies, infected meat, or by aerosol, and thus is a potential bioterrorism agent. This organism has a high infectivity rate, and can invade phagocytic and nonphagocytic cells, multiplying rapidly. Once within a macrophage, the organism can escape the phagosome and live in the cytosol. It is an aquatic organism, and can be found living inside protozoans, similar to what is observed with Legionella.