Pre_GI: SWBIT SVG BLASTP

Query: NC_009505:264963 Brucella ovis ATCC 25840 chromosome I, complete sequence

Lineage: Brucella ovis; Brucella; Brucellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: This strain was isolated from sheep tissue in Australia. Causes brucellosis in sheep. This organism specifically affects sheep, causing ovine brucellosis which results in significant economic losses. Infection by the organism can cause infertility in rams as the bacterium preferentially colonizes the genital tract, and causes inflammation of the epididymis which leads to necrotic lesions and a decrease in sperm numbers and motility. This bacterium, like other Brucella, is an intracellular pathogen that infects phagocytic cells such as macrophages. Bacterial cells produces a lipopolysaccharide that lacks O-antigen side chains, which results in a rough colony phenotype, and aids in differentiation as compared to other Brucella.

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BLASTP Alignment.txt

Subject: NC_009802:1570215 Campylobacter concisus 13826, complete genome

Lineage: Campylobacter concisus; Campylobacter; Campylobacteraceae; Campylobacterales; Proteobacteria; Bacteria

General Information: Campylobacter concisus 13826 is a gastrointestinal clinical isolate. Members of this genus are one of the most common causes of bacterial gastroenteritis (campylobacteriosis). Usually the symptoms are abdominal pain, fever, diarrhea, and cramps, but the illness can sometimes be fatal and some infected individuals develop a syndrome (Guillain-Barre) in which the nerves connecting the spinal cord to the brain are damaged. C. jejuni is the main cause of campylobacteriosis, but other species can also cause infection, including C. coli, C. upsaliensis, and C. concisus. Campylobacter concisus was first isolated from the human oral cavity in cases of gingivitis; however the role it plays in periodontal disease is unclear. This organism has also been isolated from children and immunocompromised patients with gastrointestinal disease. C. concisus is a genetically diverse species, comprised of at least four genomospecies.