Pre_GI: SWBIT SVG BLASTP

Query: NC_009488:327285 Orientia tsutsugamushi str. Boryong, complete genome

Lineage: Orientia tsutsugamushi; Orientia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This strain was isolated from a human in 1995 in Boryong, Korea. Causal agent of scrub typhus. This organism is the causative agent of scrub typhus, and like other members of the Rickettsiales is an obligate intracellular organism. Scrub typhus, which occurs in rural and agricultural areas, is one of the most common infectious diseases in southeast Asia where an estimated 1 million cases occur each year. Many cases are mild, but if left untreated, a variety of serious illnesses can arise and fatality rates can range from 1-35%. Transmission occurs via an insect vector through the bite of the larval trombiculid mite (chiggers). The bacterium is transmitted transovarially in mites (from females to their offspring).

Subject: NC_014014:153837 Mycoplasma crocodyli MP145 chromosome, complete genome

Lineage: Mycoplasma crocodyli; Mycoplasma; Mycoplasmataceae; Mycoplasmatales; Tenericutes; Bacteria

General Information: Mycoplasma crocodyli was isolated from the joint of a crocodile with exudative polyarthritis. The siblingspecies of M. crocodyli, Mycoplasma alligatoris causes acute lethalprimary infection of susceptible hosts, notably American alligators.This pathogen is studied to understand the mechanisms and evolutionaryorigins of that virulence. A genome survey indicated that M. alligatorisuses sialidase (Nanl) and hyaluronidase (NagH) to generate fuel forglycolysis from host cell glycans. M. crocodyli, which does not causedisease in American alligators, possesses NagH but not Nanl, so damageto the host's extracellular matrix alone cannot explain the particularvirulence of M. alligatoris.