Pre_GI: SWBIT SVG BLASTP

Query: NC_009488:327285 Orientia tsutsugamushi str. Boryong, complete genome

Lineage: Orientia tsutsugamushi; Orientia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This strain was isolated from a human in 1995 in Boryong, Korea. Causal agent of scrub typhus. This organism is the causative agent of scrub typhus, and like other members of the Rickettsiales is an obligate intracellular organism. Scrub typhus, which occurs in rural and agricultural areas, is one of the most common infectious diseases in southeast Asia where an estimated 1 million cases occur each year. Many cases are mild, but if left untreated, a variety of serious illnesses can arise and fatality rates can range from 1-35%. Transmission occurs via an insect vector through the bite of the larval trombiculid mite (chiggers). The bacterium is transmitted transovarially in mites (from females to their offspring).

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BLASTP Alignment.txt

Subject: NC_009900:1011000 Rickettsia massiliae MTU5, complete genome

Lineage: Rickettsia massiliae; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: Rickettsia massiliae MTU5 was isolated from the tick Rhipicephalus turanicus collected from horses in Le Sambuc, Bouches-du Rhone, France. Members of this genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens. In both groups, the bacteria are transmitted via an insect, usually a tick, to a host organism where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Rickettsia massiliae is a member of the spotted fever group of the Rickettsiales and has been isolated from ticks in Europe and Africa. Rickettsia massiliae does not appear to cause disease in humans.