Pre_GI: SWBIT SVG BLASTP

Query: NC_009487:921884 Staphylococcus aureus subsp. aureus JH9 chromosome, complete

Lineage: Staphylococcus aureus; Staphylococcus; Staphylococcaceae; Bacillales; Firmicutes; Bacteria

General Information: A series of isogenic methicillin-resistant (MRSA) strains were isolated from a patient undergoing vancomycin treatment. Causes skin infections. Staphylcocci are generally found inhabiting the skin and mucous membranes of mammals and birds. Some members of this genus can be found as human commensals and these are generally believed to have the greatest pathogenic potential in opportunistic infections. This organism is a major cause of nosocomial (hospital-acquired) and community-acquired infections. S. aureus continues to be a major cause of mortality and is responsible for a variety of infections including, boils, furuncles, styes, impetigo and other superficial skin infections in humans. Also known to cause more serious infections particularly in the chronically ill or immunocompromised. The ability to cause invasive disease is associated with persistance in the nasal cavity of a host.

Subject: NC_012466:1754388 Streptococcus pneumoniae JJA, complete genome

Lineage: Streptococcus pneumoniae; Streptococcus; Streptococcaceae; Lactobacillales; Firmicutes; Bacteria

General Information: This organism is a member of the normal human nasopharyngeal flora. There are more than 85 different antigenic types of S. pneumoniae, which are classified based on their capsule antigens. This organism is also the most common cause of sinusitis, acute bacterial otitis media, and conjunctivitis beyond early childhood. S. pneumoniae is also known to cause pneumonia, meningitis, and bacteremia. Streptococci are Gram-positive, non-motile, non-spore forming, catalase-negative cocci that occur in pairs or chains. Members of this genus vary widely in pathogenic potential. Most streptococci are facultative anaerobes, and some are obligate anaerobes.