Query: NC_009484:2442923 Acidiphilium cryptum JF-5 chromosome, complete genome Lineage: Acidiphilium cryptum; Acidiphilium; Acetobacteraceae; Rhodospirillales; Proteobacteria; Bacteria General Information: Acidiphilium cryptum strain JF-5 was isolated under iron-reducing conditions from coal mine lake sediment and is able to grow by coupling the reduction of iron to the oxidation of glucose. Iron-reducing acidophile. Acidiphilium cryptum was first isolated from a supposedly pure culture of Thiobacillus ferrooxidans. This organism, a heterotrophic acidophile, has been isolated from acid mine drainage, hydrothermal vent water, and other acidic mineral environments.
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General Information: First isolated in 1960 in Oxford, England, as an airborne contaminant growing on methylamine. This strain can grow on methylamine or methanol, but not methane. This organism is capable of growth on one-carbon compounds such as methanol. Methanol is oxidized to formaldehyde which is then used metabolically to generate either energy or biomass. These bacteria are commonly found in the environment, especially associated with plants which produce methanol when metabolizing pectin during cell wall synthesis. At least 25 genes are required for this complex process of converting methanol to formaldehyde and this specialized metabolic pathway is of great interest.