Query: NC_009465:224564 Candidatus Vesicomyosocius okutanii HA, complete genome
Lineage: Calyptogena okutanii thioautotrophic gill symbiont; sulfur-oxidizing symbionts; ; sulfur-oxidizing symbionts; Proteobacteria; Bacteria
General Information: This strain was collected off Hatsushima island in Sagami Bay, Japan. Calyptogena okutanii (deep-sea clam) thioautotrophic gill symbiont. The bivalve marine species Calyptogena okutanii depends on sulfur-oxidizing symbiotic bacteria housed in its gill tissues for its sole nutritional support. The symbiont is transmitted vertically between generations via the clam's eggs. This anaerobic symbiosis oxidizes hydrogen sulfide as an energy source and fixes carbon dioxide into organic compounds.
Subject: NC_006570:24636 Francisella tularensis subsp. tularensis Schu 4, complete genome
Lineage: Francisella tularensis; Francisella; Francisellaceae; Thiotrichales; Proteobacteria; Bacteria
General Information: This subspecies is virulent in humans, and the strain is a clinical isolate that is also virulent in an animal model. Originally isolated from a human case of tularemia in 1951. There are a large number of insertion sequences including a mariner element, which is a transposon typically found in eukaryotes and is the first instance of this element to be found in a microbe, which may have acquired it during transit through one of the insect vectors. Causative agent of tularemia. This organism was first identified by Edward Francis as the causative agent of a plague-like illness that affected squirrels in Tulare county in California in the early part of the 20th century. The organism now bears his name. The disease, which has been noted throughout recorded history, can be transmitted to humans by infected ticks or deerflies, infected meat, or by aerosol, and thus is a potential bioterrorism agent. This organism has a high infectivity rate, and can invade phagocytic and nonphagocytic cells, multiplying rapidly. Once within a macrophage, the organism can escape the phagosome and live in the cytosol. It is an aquatic organism, and can be found living inside protozoans, similar to what is observed with Legionella.