Pre_GI: SWBIT SVG BLASTP

Query: NC_009442:277392 Streptococcus suis 05ZYH33 chromosome, complete genome

Lineage: Streptococcus suis; Streptococcus; Streptococcaceae; Lactobacillales; Firmicutes; Bacteria

General Information: Isolated from a human in Ziyang County, China, 2005. Causative agent of meningitis, endocarditis, septicemia and arthritis in swine. Streptococci are Gram-positive, nonmotile, nonsporeforming, catalase-negative cocci that occur in pairs or chains. Members of this genus vary widely in pathogenic potential. Most streptococci are facultative anaerobes, and some are obligate anaerobes. Serologic grouping is based on antigenic differences in cell wall carbohydrates, in cell wall pili-associated protein, and in the polysaccharide capsule in group B streptococci. Streptococcus suis is a pathogen of pigs and is responsible for a variety of diseases including meningitis, arthritis and pneumonia. Occasionally this organism can infect humans causing septicemia, meningitis and endocarditis.

Subject: NC_000963:205546 Rickettsia prowazekii str. Madrid E, complete genome

Lineage: Rickettsia prowazekii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This strain is an egg-passaged attentuated avirulent strain that has been used as a live vaccine and was originally isolated from a typhus patient in Madrid. This species is the causal agent of typhus. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host.