Query: NC_009441:395427 Flavobacterium johnsoniae UW101 chromosome, complete genome
Lineage: Flavobacterium johnsoniae; Flavobacterium; Flavobacteriaceae; Flavobacteriales; Bacteroidetes; Bacteria
General Information: Flavobacterium johnsoniae ATCC 17061 was isolated from soil in England. Common soil and freshwater bacterium that is motile by gliding. Flavobacterium johnsoniae, formerly Cytophaga johnsonae, is common in soil and freshwater. This organism belongs to a large group of related environmental microorganisms that are characterized by the ability to utilize a wide variety of naturally occurring complex compounds, such as chitin, cellulose, and lignin.
Subject: NC_011896:2240990 Mycobacterium leprae Br4923, complete genome
Lineage: Mycobacterium leprae; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria
General Information: This strain was isolated from a human skin biopsy in Brazil, and passaged in nude mice and armadillos. The bacterium is a close relative of M. tuberculosis. However, compared to the latter, the genome of M. leprae is smaller due to reductive genome evolution, with many important metabolic activities including siderophore production, part of the oxidative chain, most of the microaerophilic and anaerobic respiratory chains, and numerous catabolic systems and their regulatory circuits eliminated due to extensive recombination events between dispersed repetitive sequences. It is evident that this species has undergone massive genome reduction over time as a result of its parasitic nature, discarding more than half its genes and rendering it the most striking example of genome reduction in a microbial pathogen.