Query: NC_009441:395427 Flavobacterium johnsoniae UW101 chromosome, complete genome Lineage: Flavobacterium johnsoniae; Flavobacterium; Flavobacteriaceae; Flavobacteriales; Bacteroidetes; Bacteria General Information: Flavobacterium johnsoniae ATCC 17061 was isolated from soil in England. Common soil and freshwater bacterium that is motile by gliding. Flavobacterium johnsoniae, formerly Cytophaga johnsonae, is common in soil and freshwater. This organism belongs to a large group of related environmental microorganisms that are characterized by the ability to utilize a wide variety of naturally occurring complex compounds, such as chitin, cellulose, and lignin.
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General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. Rickettsia typhi causes murine typhus and is an obligate intracellular pathogen that infects both the flea vector and hosts such as human, rat, and mouse. In the flea vector, the bacterium penetrates the gut epithelial barrier and is found in the feces which become infective.