Query: NC_009438:2939478 Shewanella putrefaciens CN-32 chromosome, complete genome
Lineage: Shewanella putrefaciens; Shewanella; Shewanellaceae; Alteromonadales; Proteobacteria; Bacteria
General Information: Shewanella putrefaciens is a Gram-negative bacterium. It has been isolated from marine environments, as well as from anaerobic sandstone in the Morrison formation in New Mexico, USA. S. putrefaciens is also a facultative anaerobe with the ability to reduce iron and manganese metabolically; that is, it can use iron and manganese as the terminal electron acceptor in the electron transport chain (in contrast to obligate aerobes which must use oxygen for this purpose). It is also one of the organisms associated with the odor of rotting fish, as it is a marine organism which produces trimethylamines (hence the species name putrefaciens, from putrid). This genus includes species that inhabit a wide range of environments and are capable of utilizing a wide variety of electron acceptors during anaerobic respiration including some insoluble metal oxides while using very few carbon sources such as lactate or acetate. This group of organisms have been studied extensively for their electron transport systems. This species, along with Shewanella algae, are the only Shewanella spp. to be found in clinical speciments. Normally found in marine environments in warmer temperatures, infections seem to occur more frequently in countries with a warm climate and in other countries during warm summer months.
Subject: NC_004631:862002 Salmonella enterica subsp. enterica serovar Typhi Ty2, complete
Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria
General Information: This pathogenic strain of Salmonella typhi was isolated in the early 1970s. It contains no multidrug resistance plasmids and has been used for vaccine development. This serovar is a human-specific organism that causes the life-threatening illness Typhoid fever which is acquired by coming into contact with contaminated food or water. Annually, 17 million people are infected, with 600,000 fatalities, mostly in developing countries. It contains multiple fimbrial operons that may be used to create extracellular appendages for attachment and entry into host intestinal epithelial cells. Causes enteric infections. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.