Query: NC_009437:283382 Caldicellulosiruptor saccharolyticus DSM 8903, complete genome Lineage: Caldicellulosiruptor saccharolyticus; Caldicellulosiruptor; Thermoanaerobacterales Family III; Thermoanaerobacterales; Firmicutes; Bacteria General Information: Caldicellulosiruptor saccharolyticus is a cellulolytic thermphile. This organism produces thermostable cellulases, which are of use in paper manufacturing. Caldicellulosiruptor saccharolyticus DSM 8903 was isolated from a hot spring in New Zealand.
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General Information: Causes bovine brucellosis. They are highly infectious, and can be spread through contact with infected animal products or through the air, making them a potential bioterrorism agent. Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Virulence may depend on a type IV secretion system which may promote intracellular growth by secreting important effector molecules. This organism was first noticed on the island of Malta. It is the primary cause of bovine brucellosis, which results in enormous (billions of dollars) economic losses due primarily to reproductive failure and food losses. In man, it causes undulant fever, a long debilitating disease that is treated by protracted administration of antibiotics.