Pre_GI: SWBIT SVG BLASTP

Query: NC_009257:963536 Francisella tularensis subsp. tularensis WY96-3418 chromosome,

Lineage: Francisella tularensis; Francisella; Francisellaceae; Thiotrichales; Proteobacteria; Bacteria

General Information: This strain was isolated from a human finger wound. Causative agent of tularemia. This organism was first identified by Edward Francis as the causative agent of a plague-like illness that affected squirrels in Tulare county in California in the early part of the 20th century. The organism now bears his name. The disease, which has been noted throughout recorded history, can be transmitted to humans by infected ticks or deerflies, infected meat, or by aerosol, and thus is a potential bioterrorism agent. This organism has a high infectivity rate, and can invade phagocytic and nonphagocytic cells, multiplying rapidly. Once within a macrophage, the organism can escape the phagosome and live in the cytosol. It is an aquatic organism, and can be found living inside protozoans, similar to what is observed with Legionella.

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Subject: NC_015722:4539 Candidatus Midichloria mitochondrii IricVA chromosome, complete

Lineage: Midichloria mitochondrii; Midichloria; Candidatus Midichloriaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: Candidatus Midichloria mitochondrii is a symbiont of the tick Ixodes ricinus. The importance of this organism is two-fold. this symbiont is the only bacterium described that is able of invading the mitochondria of animals. The host Ixodes ricinus is a vector of a number of human diseases.