Query: NC_009256:2725836 Burkholderia vietnamiensis G4 chromosome 1, complete sequence Lineage: Burkholderia vietnamiensis; Burkholderia; Burkholderiaceae; Burkholderiales; Proteobacteria; Bacteria General Information: B. vietnamiensis strain G4 (formerly B.cepacia strain R1808) is the best trichloroethene (TCE) co-oxidizing strain yet discovered, having been isolated from an industrial waste treatment facility at Pensacola Naval Air Station, Florida, U.S.A. Burkholderia vietnamiensis is a member of the Burkholderia cepacia complex which contains a number of closely related Burkholderia species. Burkholderia vietnamiensis is commonly isolated from soil and water and has been studied as a plant growth promoting bacterium and as a bioremediation agent for aromatic hydrocarbons such as benzene and tolulene.
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General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. Rickettsia typhi causes murine typhus and is an obligate intracellular pathogen that infects both the flea vector and hosts such as human, rat, and mouse. In the flea vector, the bacterium penetrates the gut epithelial barrier and is found in the feces which become infective.