Query: NC_009142:6086000 Saccharopolyspora erythraea NRRL 2338, complete genome Lineage: Saccharopolyspora erythraea; Saccharopolyspora; Pseudonocardiaceae; Actinomycetales; Actinobacteria; Bacteria General Information: Source of the antibiotic erythromycin. Saccharopolyspora erythraea is the soil bacterium that produces the industrially important antibiotic erythromycin A. Erythromycin is a clinically important and potent macrolide antibiotic. It is used to treat infections caused by several prokaryotic pathogens such as Streptococcus, Staphylococcus, Mycoplasma, Ureaplasma, Chlamydia and Legionella. Production of this antibiotic is lower than others in the same class, such as penicillin or cephalosporin, which has led to the development of a genetic system to attempt to enhance the production of erythromycin.
- Sequence; - BLASTP hit: hover for score (Low score = Light, High score = Dark); - hypothetical protein; - cds: hover for description
General Information: Arthrobacter chlorophenolicus A6 (DSM 12829) was isolated from soil at Fort Collins, Colorado, USA and is able to use 4-chlorophenol as a sole source of carbon and energy. This organism can degrade 4-chlorophenol in soil at temperatures ranging from 5 to 28 degrees C making it a good candidate for bioremediation. Arthrobacter chlorophenolicus can degrade high concentrations of para-substituted phenols, such as 4-chlorophenol and 4-nitrophenol and can survive under harsh conditions, such as cold temperature and during starvation in soil.