Query: NC_009142:2801517 Saccharopolyspora erythraea NRRL 2338, complete genome Lineage: Saccharopolyspora erythraea; Saccharopolyspora; Pseudonocardiaceae; Actinomycetales; Actinobacteria; Bacteria General Information: Source of the antibiotic erythromycin. Saccharopolyspora erythraea is the soil bacterium that produces the industrially important antibiotic erythromycin A. Erythromycin is a clinically important and potent macrolide antibiotic. It is used to treat infections caused by several prokaryotic pathogens such as Streptococcus, Staphylococcus, Mycoplasma, Ureaplasma, Chlamydia and Legionella. Production of this antibiotic is lower than others in the same class, such as penicillin or cephalosporin, which has led to the development of a genetic system to attempt to enhance the production of erythromycin.
- Sequence; - BLASTP hit: hover for score (Low score = Light, High score = Dark); - hypothetical protein; - cds: hover for description
General Information: Country: USA; Environment: Sludge, Fresh water; Isolation: Industrial sludge contaminated; Temp: Mesophile; Temp: 30C. Pseudonocardia members are abundant in diverse environments, and are known to degrade a variety of pollutants. These bacteria are also important in biocatalysis applications and in the production of antibiotics. Pseudonocardia dioxanivorans was first isolated from 1,4-dioxane containing sludge. This organism is able to grow using 1,4-dioxane, a toxic compound used as an industrial solvent, as the sole carbon source.