Query: NC_009142:2565561 Saccharopolyspora erythraea NRRL 2338, complete genome Lineage: Saccharopolyspora erythraea; Saccharopolyspora; Pseudonocardiaceae; Actinomycetales; Actinobacteria; Bacteria General Information: Source of the antibiotic erythromycin. Saccharopolyspora erythraea is the soil bacterium that produces the industrially important antibiotic erythromycin A. Erythromycin is a clinically important and potent macrolide antibiotic. It is used to treat infections caused by several prokaryotic pathogens such as Streptococcus, Staphylococcus, Mycoplasma, Ureaplasma, Chlamydia and Legionella. Production of this antibiotic is lower than others in the same class, such as penicillin or cephalosporin, which has led to the development of a genetic system to attempt to enhance the production of erythromycin.
- Sequence; - BLASTP hit: hover for score (Low score = Light, High score = Dark); - hypothetical protein; - cds: hover for description
General Information: Chemoheterotrophic obligate extreme halophilic archeon. This microbe (strain ATCC 700922) is an obligately halophilic archeon that has adapted to growth under conditions of extremely high salinity. Motility is via tufts of polar flagella and intracellular gas vesicles are used for buoyancy. This organism grow aerobically and its ease of culturing combined with the availability of established methods of genetic manipulation in the laboratory make it an ideal model organism for study of the archaea.