Query: NC_009142:2480608 Saccharopolyspora erythraea NRRL 2338, complete genome Lineage: Saccharopolyspora erythraea; Saccharopolyspora; Pseudonocardiaceae; Actinomycetales; Actinobacteria; Bacteria General Information: Source of the antibiotic erythromycin. Saccharopolyspora erythraea is the soil bacterium that produces the industrially important antibiotic erythromycin A. Erythromycin is a clinically important and potent macrolide antibiotic. It is used to treat infections caused by several prokaryotic pathogens such as Streptococcus, Staphylococcus, Mycoplasma, Ureaplasma, Chlamydia and Legionella. Production of this antibiotic is lower than others in the same class, such as penicillin or cephalosporin, which has led to the development of a genetic system to attempt to enhance the production of erythromycin.
- Sequence; - BLASTP hit: hover for score (Low score = Light, High score = Dark); - hypothetical protein; - cds: hover for description
General Information: This strain was isolated from soil contaminated with gamma-hexachlorocyclohexane (lindane: a toxic insecticide) in Japan. Polychlorinated biphenyl degrading bacterium. Rhodococcus jostii is capable of degrading a wide variety of polychlorinated biphenyls (PCBs), which are toxic compounds produced by industry, and is studied extensively for this reason. This microbe is being examined thoroughly under different environmental conditions in order to better understand metabolic pathways and gene functions.