Pre_GI: SWBIT SVG BLASTP

Query: NC_009142:7820251 Saccharopolyspora erythraea NRRL 2338, complete genome

Lineage: Saccharopolyspora erythraea; Saccharopolyspora; Pseudonocardiaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Source of the antibiotic erythromycin. Saccharopolyspora erythraea is the soil bacterium that produces the industrially important antibiotic erythromycin A. Erythromycin is a clinically important and potent macrolide antibiotic. It is used to treat infections caused by several prokaryotic pathogens such as Streptococcus, Staphylococcus, Mycoplasma, Ureaplasma, Chlamydia and Legionella. Production of this antibiotic is lower than others in the same class, such as penicillin or cephalosporin, which has led to the development of a genetic system to attempt to enhance the production of erythromycin.

Subject: NC_006513:1695487 Azoarcus sp. EbN1, complete genome

Lineage: Aromatoleum aromaticum; Aromatoleum; Rhodocyclaceae; Rhodocyclales; Proteobacteria; Bacteria

General Information: First isolated from sediment contaminated with ethylbenzene, this organism is capable of growing on crude oil, using polar aromatic compounds such as benzoate under both oxic and anoxic conditions. It is currently being evaluated for use in aromatic hydrocarbon bioremediation projects. Aromatic hydrocarbon-degrading bacterium. Capable of metabolizing various aromatic hydrocarbons, including toluene and ethylbenzene and may be of use in bioremediation.