Pre_GI: SWBIT SVG BLASTP

Query: NC_009142:2565561 Saccharopolyspora erythraea NRRL 2338, complete genome

Lineage: Saccharopolyspora erythraea; Saccharopolyspora; Pseudonocardiaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Source of the antibiotic erythromycin. Saccharopolyspora erythraea is the soil bacterium that produces the industrially important antibiotic erythromycin A. Erythromycin is a clinically important and potent macrolide antibiotic. It is used to treat infections caused by several prokaryotic pathogens such as Streptococcus, Staphylococcus, Mycoplasma, Ureaplasma, Chlamydia and Legionella. Production of this antibiotic is lower than others in the same class, such as penicillin or cephalosporin, which has led to the development of a genetic system to attempt to enhance the production of erythromycin.

Subject: NC_013411:3314799 Geobacillus sp. Y412MC61, complete genome

Lineage: Geobacillus; Geobacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: Isolation: Obsidian Hot Spring in Yellowstone; Country: USA; Temp: Mesophile. Recent rDNA analysis and DNA-DNA hybridization studies using spore-forming thermophilic subsurface isolates from formation waters of oilfields in Russia, Kazakhstan and China provided enough evidence to define the phylogenetically distinct, physiologically and morphologically consistent taxon Geobacillus. Geobacillus species are chemo-organotrophic, obligately thermophilic, neutrophilic, motile, spore-forming, aerobic or facultatively anaerobic.