Query: NC_009075:2428248 Burkholderia pseudomallei 668 chromosome II, complete sequence Lineage: Burkholderia pseudomallei; Burkholderia; Burkholderiaceae; Burkholderiales; Proteobacteria; Bacteria General Information: Isolated from the blood of a 53 year old male patient with severe melioidosis encephalomyelitis in Darwin, Australia in 1995. This species is an opportunistic pathogen and can cause pneumonia, bacteremia, and melioidosis. It is normally found in terrestrial environments and has been recovered from rice paddies and moist tropical soil. It is endemic in Asia and Australia, but can be found in other parts of the world. The organism can exist intracellularly and can spread through the bloodstream (bacteremia).
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General Information: This bacterium is named after Simona Kahane who discovered the organism as a contaminant in cell cultures at Ber Sheva, in the Negev Desert, Israel, in 1993. Simkania negevensis is a member of the order Chlamydiales and can reside intracellularly and has a slow prolonged developmental cycle. It has a wide geographical and environmental distribution and is associated with pneumonia, bronchiolitis and chronic obstructive pulmonary disease, furthermore, it is completely resistant to penicillin and to bacitracin. The natural hosts of Simkania negevensis bacteria might be amoebae.