Pre_GI: SWBIT SVG BLASTP

Query: NC_009073:1708544 Pyrobaculum calidifontis JCM 11548, complete genome

Lineage: Pyrobaculum calidifontis; Pyrobaculum; Thermoproteaceae; Thermoproteales; Crenarchaeota; Archaea

General Information: This organism is a facultatively anaerobic, hyperthermophilic archaeon, first isolated from a hot spring in the Philippines. Pyrobaculum calidifontis cannot use sulfur compounds for anaerobic growth and is only able to grow anaerobically using nitrate as an electron acceptor.

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Subject: NC_013316:1 Clostridium difficile R20291, complete genome

Lineage: Peptoclostridium difficile; Peptoclostridium; Peptostreptococcaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium difficile R20291 was isolated in Stoke Mandeville Hospital, UK in 2006 and is closely related to the North American hypervirulent BI strains. Clostridium difficile, a Gram-positive, spore-forming anaerobic bacterium, is the leading cause of infectious diarrhea among patients in hospitals worldwide, causing C. difficile infection (CDI). An important nosocomial pathogen, it is frequently associated with antibiotic treatment and causes diseases ranging from antibiotic-associated diarrhea to life-threatening pseudomembraneous colitis.