Query: NC_008835:1827905 Burkholderia mallei NCTC 10229 chromosome I, complete sequence
Lineage: Burkholderia mallei; Burkholderia; Burkholderiaceae; Burkholderiales; Proteobacteria; Bacteria
General Information: Causes glanders in horses. This organism is rarely associated with human infection, and is more commonly seen in domesticated animals such as horses, donkeys, and mules where it causes glanders, a disease first described by Aristotle. The pathogen is host-adapted and is not found in the environment outside of its host. Rapid-onset pneumonia, bacteremia (spread of the organism through the blood), pustules, and death are common outcomes during infection. No vaccine exists for this potentially dangerous organism.
Subject: NC_008544:615448 Burkholderia cenocepacia HI2424 chromosome 3, complete sequence
Lineage: Burkholderia cenocepacia; Burkholderia; Burkholderiaceae; Burkholderiales; Proteobacteria; Bacteria
General Information: This organism (HI2424; BCC1) was isolated as part of a study to find this organism in natural environments. Samples taken from fields that were planted with onions in New York in 1999 and 2000 were examined and it was discovered that isolates were the same as ones that can infect CF patients. This species (genomovar III) is part of the Burkholderia cepacia complex, which consists of 9 closely related species, also known as genomovars. These organisms are commonly found in soil and all are opportunistic pathogens espcially in cystic fibrosis patients.