Query: NC_008817:1443983 Prochlorococcus marinus str. MIT 9515, complete genome Lineage: Prochlorococcus marinus; Prochlorococcus; Prochlorococcaceae; Prochlorales; Cyanobacteria; Bacteria General Information: This strain was collected from the surface waters of the Equatorial Pacific. Marine cyanobacterium. This non-motile bacterium is a free-living marine organism that is one of the most abundant, as well as the smallest, on earth, and contributes heavily to carbon cycling in the marine environment. This cyanobacterium grows in areas of nitrogen and phosphorus limitation and is unique in that it utilizes divinyl chlorophyll a/b proteins as light-harvesting systems instead of phycobiliproteins. These pigments allow harvesting of light energy from blue wavelengths at low light intensity.
- Sequence; - BLASTP hit: hover for score (Low score = Light, High score = Dark); - hypothetical protein; - cds: hover for description
General Information: Bartonella henselae str. Houston-1 (ATCC 49882) was isolated from human blood in Houston Texas. Causative agent of cat scratch fever. This group of alpha proteobacteria are unique among pathogens in that they cause angiogenic lesions. This organism was identified as the causative agent of cat scratch fever, a disease found commonly in children or in immunocompromised adults. The proliferation of the vascular endothelium (bacillary angiomatosis) is characterisitic of Bartonella infection and results in multiplication of the bacterium's host cells. Infected macrophages are stimulated to release vascular endothelial growth factor (VEGF) and interleukin 1 beta, both of which promote angiogenesis. Endothelial cells are also stimulated to grow and divide by direct contact with bacterial cells. In addition, programmed cell death (apoptosis) of endothelial cells is inhibited, combatting a common mechanism eukaryotic cells use to deal with bacterial infection. Other pathogenicity factors include pili and outer membrane adhesins for attachment to host cells.