Query: NC_008783:671349 Bartonella bacilliformis KC583, complete genome Lineage: Bartonella bacilliformis; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria General Information: Cauative agent of Carrion's disease. Like other members of this genus, Bartonella bacilliformis is an obligate intracellular parasite, which infects red blood cells. Bartonella bacilliformis is the causative agent of Carrion's disease, also called Oroya fever. This disease is found in the western Andes of South America, and is transmitted through an insect vector. Carrion's disease is characterized by an acute, febrile, anemia with a mortality of 40 to 90%. The anemic phase may be followed by a milder secondary episode, characterized by wart-like skin lesions.
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General Information: Gram-negative, microaerophilic, flagellate, spiral bacterium, Campylobacter species are the leading cause of food-borne gastroenteritis in developed countries. Infection with C. jejuni is the most frequent antecedent to a form of neuromuscular paralysis known as Guillain-Barre syndrome (GBS). Strain ICDCCJ07001 was isolated following a GBS outbreak in Shuangyang, a town in northern China in 2007, from a severely affected 15 year-old girl GBS patient who had been on a ventilator for 180 days. Her clinical symptoms were motor axonal neuropathy. This organism is the leading cause of bacterial food poisoning (campylobacteriosis) in the world, and is more prevalent than Salmonella enteritis (salmonellosis). Found throughout nature, it can colonize the intestines of both mammals and birds, and transmission to humans occurs via contaminated food products. This organism can invade the epithelial layer by first attaching to epithelial cells, then penetrating through them. Systemic infections can also occur causing more severe illnesses.