Query: NC_008782:867344 Acidovorax sp. JS42, complete genome Lineage: Acidovorax; Acidovorax; Comamonadaceae; Burkholderiales; Proteobacteria; Bacteria General Information: Acidovorax sp. JS42, formerly Pseudomonas sp. JS42, was isolated from nitrobenzene-contaminated sediment and is capable of using 2-nitrotolulene as a sole carbon and energy source. 2-nitrotolulene, a nitroaromatic compound, is used in the manufacture of dyes, pigments and explosives. Nitroaromatic compounds, which contain an aromatic ring with one or more nitro groups attached, are a significant contaminant in industrial soils. Acidovorax sp. JS42 degrades 2-nitrotolulene by first removing the nitro moiety producing 3-methylcatechol. The enzyme involved in this process, 2-nitrotolulene dioxygenase, has been purified and characterized.
- Sequence; - BLASTP hit: hover for score (Low score = Light, High score = Dark); - hypothetical protein; - cds: hover for description
General Information: First isolated in 1960 in Oxford, England, as an airborne contaminant growing on methylamine. This strain can grow on methylamine or methanol, but not methane. This organism is capable of growth on one-carbon compounds such as methanol. Methanol is oxidized to formaldehyde which is then used metabolically to generate either energy or biomass. These bacteria are commonly found in the environment, especially associated with plants which produce methanol when metabolizing pectin during cell wall synthesis. At least 25 genes are required for this complex process of converting methanol to formaldehyde and this specialized metabolic pathway is of great interest.