Query: NC_008782:1510000 Acidovorax sp. JS42, complete genome Lineage: Acidovorax; Acidovorax; Comamonadaceae; Burkholderiales; Proteobacteria; Bacteria General Information: Acidovorax sp. JS42, formerly Pseudomonas sp. JS42, was isolated from nitrobenzene-contaminated sediment and is capable of using 2-nitrotolulene as a sole carbon and energy source. 2-nitrotolulene, a nitroaromatic compound, is used in the manufacture of dyes, pigments and explosives. Nitroaromatic compounds, which contain an aromatic ring with one or more nitro groups attached, are a significant contaminant in industrial soils. Acidovorax sp. JS42 degrades 2-nitrotolulene by first removing the nitro moiety producing 3-methylcatechol. The enzyme involved in this process, 2-nitrotolulene dioxygenase, has been purified and characterized.
- Sequence; - BLASTP hit: hover for score (Low score = Light, High score = Dark); - hypothetical protein; - cds: hover for description
General Information: Causes glanders in horses. This organism is rarely associated with human infection, and is more commonly seen in domesticated animals such as horses, donkeys, and mules where it causes glanders, a disease first described by Aristotle. The pathogen is host-adapted and is not found in the environment outside of its host. Rapid-onset pneumonia, bacteremia (spread of the organism through the blood), pustules, and death are common outcomes during infection. No vaccine exists for this potentially dangerous organism.