Pre_GI: SWBIT SVG BLASTP

Query: NC_008611:1015138 Mycobacterium ulcerans Agy99, complete genome

Lineage: Mycobacterium ulcerans; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This organism causes Buruli ulcer and is the third most common mycobacterial pathogen after Mycobacterium tuberculosis and Mycobacterium leprae. The disease has increased dramatically through central and West Africa since the late 1980s. Causative agent of Buruli and Bairnsdale ulcer. Infection by Mycobacterium ulcerans causes the formation of skin ulcers which, if left untreated, can lead to extensive scarring and/or amputation. Mycobacterium ulcerans produces a cytotoxin, mycolactone, which causes the destruction of skin tissue seen in this disease. This organism is resistant to antibiotics and treatment involves the surgical removal of infected tissues.

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Subject: NC_014158:2561441 Tsukamurella paurometabola DSM 20162 chromosome, complete genome

Lineage: Tsukamurella paurometabola; Tsukamurella; Tsukamurellaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Isolation: Cases of systemic infection, usually in association with other diseases; Temp: Mesophile; Habitat: Sludge, Soil. Tsukamurella paurometabola, formerly Corynebacterium paurometabolum, was isolated from from mycetomes and ovaries of bed bugs (Cimex lectularius) and has also been found in soil and sludge. This organism has been isolated from cases of systemic infection, usually in association with other diseases.