Pre_GI: SWBIT SVG BLASTP

Query: NC_008611:1015138 Mycobacterium ulcerans Agy99, complete genome

Lineage: Mycobacterium ulcerans; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This organism causes Buruli ulcer and is the third most common mycobacterial pathogen after Mycobacterium tuberculosis and Mycobacterium leprae. The disease has increased dramatically through central and West Africa since the late 1980s. Causative agent of Buruli and Bairnsdale ulcer. Infection by Mycobacterium ulcerans causes the formation of skin ulcers which, if left untreated, can lead to extensive scarring and/or amputation. Mycobacterium ulcerans produces a cytotoxin, mycolactone, which causes the destruction of skin tissue seen in this disease. This organism is resistant to antibiotics and treatment involves the surgical removal of infected tissues.

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BLASTP Alignment.txt

Subject: NC_009077:1687304 Mycobacterium sp. JLS, complete genome

Lineage: Mycobacterium; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This organism was isolated from creosote-contaminated soil from the Champion International Superfund site in Libby, Montana, USA. This microbe, along with some others collected at this site, is able to rapidly mineralize 14C-labeled pyrene. Phylogenetic studies based on the rRNA 16S gene confirmed that strains collected at this site were distinct from one another and also from other known Mycobacterium isolates.