Pre_GI: SWBIT SVG BLASTP

Query: NC_008596:6009511 Mycobacterium smegmatis str. MC2 155, complete genome

Lineage: Mycobacterium smegmatis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Causes opportunistic infections. This genus comprises a number of Gram-positive, acid-fast, rod-shaped aerobic bacteria and is the only member of the family Mycobacteriaceae within the order Actinomycetales. Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. Mycobacterium smegmatis was initially isolated from human smegma. It is associated with soft tissue lesions following trauma or surgery. It is also reported as a possible factor in penile carcinogenesis.

Subject: NC_008785:914411 Burkholderia mallei SAVP1 chromosome II, complete sequence

Lineage: Burkholderia mallei; Burkholderia; Burkholderiaceae; Burkholderiales; Proteobacteria; Bacteria

General Information: This strain is non-virulent. Causes glanders in horses. This organism is rarely associated with human infection, and is more commonly seen in domesticated animals such as horses, donkeys, and mules where it causes glanders, a disease first described by Aristotle. This organism is similar to B. pseudomallei and is differentiated by being nonmotile. The pathogen is host-adapted and is not found in the environment outside of its host. Rapid-onset pneumonia, bacteremia (spread of the organism through the blood), pustules, and death are common outcomes during infection. No vaccine exists for this potentially dangerous organism.