Query: NC_008595:1792318 Mycobacterium avium 104, complete genome

Lineage: Mycobacterium avium; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: It was derived from an AIDS patient and has been characterized for virulence in the murine model of low-dose aerosol infection in that it could colonize the lung, proliferate within the tissue and disseminate to other organs. Environmental organism which causes infections in birds and humans. This genus comprises a number of Gram-positive, acid-fast, rod-shaped aerobic bacteria and is the only member of the family Mycobacteriaceae within the order Actinomycetales. Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, Mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. Mycobacterium avium is ubiquitous in the environment, and can be found in stagnant waters and soils. This organism causes tuberculosis in birds and disseminated infections in immunocompromized humans (the elderly, children, and especially patients with AIDS). Infection results in a characteristic pulmonary disease which requires expensive drug therapy for successful treatment. Most prevalent colony morphotypes are smooth opaque, smooth transparent and rough, with the last two being the faster growers in vivo.

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BLASTP Alignment.txt

Subject: NC_008278:1472709 Frankia alni ACN14a, complete genome

Lineage: Frankia alni; Frankia; Frankiaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated from a green alder (Alnus crispa) growing in Tadoussac, Canada. These bacteria were originally linked to fungi, because of the mycelium-like filaments many of them form. This bacterium is able to establish a nitrogen-fixing symbiosis with alder (Alnus spp.) and myrtle (Myrica spp.), two pioneer plant genera of temperate regions, found on forest clearings, mine wastes, sand dunes and glacial moraines where nitrogen is the limiting factor. Frankia alni causes root hair deformation: it penetrates the cortical cells and induces the formation of nodules which resemble those induced by Rhizobium in legumes. These nodules are then colonized by vegetative hyphae (mycelium filaments) which differentiate into diazo-vesicles