Pre_GI: SWBIT SVG BLASTP

Query: NC_008570:236500 Aeromonas hydrophila subsp. hydrophila ATCC 7966, complete genome

Lineage: Aeromonas hydrophila; Aeromonas; Aeromonadaceae; Aeromonadales; Proteobacteria; Bacteria

General Information: Isolated from canned milk from the USA. Aquatic organism that can cause foodborne illnesses in humans. This organism is an enviromental bacterium that is often found in aquatic habitats, but can also be found contaminating food products. It causes a variety of diseases in both cold-blooded and warm-blooded organisms. The bacterium is becoming a problematic pathogen in humans, where it causes gastroenteritis and septicemia, mainly due to the development of antibiotic resistance by this organism. One of the major virulence factors is aerolysin, a toxin that is produced and secreted by the cell via a type II secretion apparatus. Other virulence functions include a surface layer which inhibits complement-mediated killing, type IV pili for attachment, and a set of extracellular proteases which can cause tissue damage.

Subject: NC_007426:1489677 Natronomonas pharaonis DSM 2160, complete genome

Lineage: Natronomonas pharaonis; Natronomonas; Halobacteriaceae; Halobacteriales; Euryarchaeota; Archaea

General Information: Isolated from Lake Gabara in Egypt. Extreme haloalkaliphilic archeon. Natronomonas pharaonis is able to survive at high salt and pH conditions which results in limited nitrogen availability through ammonium. In order to compensate for this, Natronomonas pharaonis has developed three systems to promote nitrogen assimilation: direct uptake of ammonia, uptake of nitrate, and uptake of urea. Another problem with high pH environments is the use of a proton gradient for the generation of ATP, which other alkaliphiles have adapted to by substitution of sodium ions for protons. However, this organism utilizes protons for ATP generation as determined by experimental data.