Pre_GI: SWBIT SVG BLASTP

Query: NC_008570:1986466 Aeromonas hydrophila subsp. hydrophila ATCC 7966, complete genome

Lineage: Aeromonas hydrophila; Aeromonas; Aeromonadaceae; Aeromonadales; Proteobacteria; Bacteria

General Information: Isolated from canned milk from the USA. Aquatic organism that can cause foodborne illnesses in humans. This organism is an enviromental bacterium that is often found in aquatic habitats, but can also be found contaminating food products. It causes a variety of diseases in both cold-blooded and warm-blooded organisms. The bacterium is becoming a problematic pathogen in humans, where it causes gastroenteritis and septicemia, mainly due to the development of antibiotic resistance by this organism. One of the major virulence factors is aerolysin, a toxin that is produced and secreted by the cell via a type II secretion apparatus. Other virulence functions include a surface layer which inhibits complement-mediated killing, type IV pili for attachment, and a set of extracellular proteases which can cause tissue damage.

Subject: NC_013416:1429881 Aggregatibacter actinomycetemcomitans D11S-1, complete genome

Lineage: Aggregatibacter actinomycetemcomitans; Aggregatibacter; Pasteurellaceae; Pasteurellales; Proteobacteria; Bacteria

General Information: Aggregatibacter actinomycetemcomitans D11S-1 was recovered from a subject with aggressive periodontitis. Aggregatibacter actinomycetemcomitans, previously Actinobacillus actinomycetemcomitans typically resides in the oral cavity of humans and animals and can cause a number of diseases. The bacterium, along with 3 other organisms, is the main culprit in periodontis, which results in devastation to the bone supporting the teeth. Adherence to oral surfaces is controlled through the tad (tight adherence) locus, which may express proteins that are involved in type IV secretion.