Query: NC_008554:3177723 Syntrophobacter fumaroxidans MPOB, complete genome
Lineage: Syntrophobacter fumaroxidans; Syntrophobacter; Syntrophobacteraceae; Syntrophobacterales; Proteobacteria; Bacteria
General Information: This organism is a syntrophic propionate-oxidizing bacterium isolated from granular sludge from an anaerobic sludge bed reactor treating sugar-beet processing wastewater. Propionate-oxidizing bacterium. This organism is able to oxidize propionate when grown in co-culture with hydrogen-consuming methanogens (syntrophic metabolism). This organism can also ferment fumarate when not in co-culture.
Subject: NC_003103:266013 Rickettsia conorii str. Malish 7, complete genome
Lineage: Rickettsia conorii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria
General Information: This strain was isolated from a human in South Africa. Causative agent for Rocky Mountain spotted fever. This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes Rocky Mountain spotted fever which can cause severe damage to the endothelial layer of major organs, including the lungs, heart, kidneys, and skeletal muscle which can result in death.