Query: NC_008510:995612 Leptospira borgpetersenii serovar Hardjo-bovis JB197 chromosome 1, Lineage: Leptospira borgpetersenii; Leptospira; Leptospiraceae; Spirochaetales; Spirochaetes; Bacteria General Information: This strain is lethal in hamsters. This strain is lethal in hamsters. This organism is a bacterial pathogen of cattle. This organism colonizes in the kidney and reproductive tracts of infected animals. There is also a risk of zoonotic infections in humans, especially those who work with cattle.
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General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.