Pre_GI: SWBIT SVG BLASTP

Query: NC_008369:514995 Francisella tularensis subsp. holarctica OSU18, complete genome

Lineage: Francisella tularensis; Francisella; Francisellaceae; Thiotrichales; Proteobacteria; Bacteria

General Information: Isolated from a beaver that died of tularemia in Oklahoma in 1978. Causative agent of tularemia. This organism was first identified by Edward Francis as the causative agent of a plague-like illness that affected squirrels in Tulare county in California in the early part of the 20th century. The organism now bears his name. The disease, which has been noted throughout recorded history, can be transmitted to humans by infected ticks or deerflies, infected meat, or by aerosol, and thus is a potential bioterrorism agent. This organism has a high infectivity rate, and can invade phagocytic and nonphagocytic cells, multiplying rapidly. Once within a macrophage, the organism can escape the phagosome and live in the cytosol. It is an aquatic organism, and can be found living inside protozoans, similar to what is observed with Legionella.

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BLASTP Alignment.txt

Subject: NC_015713:1594114 Simkania negevensis Z chromosome gsn.131, complete genome

Lineage: Simkania negevensis; Simkania; Simkaniaceae; Chlamydiales; Chlamydiae; Bacteria

General Information: This bacterium is named after Simona Kahane who discovered the organism as a contaminant in cell cultures at Ber Sheva, in the Negev Desert, Israel, in 1993. Simkania negevensis is a member of the order Chlamydiales and can reside intracellularly and has a slow prolonged developmental cycle. It has a wide geographical and environmental distribution and is associated with pneumonia, bronchiolitis and chronic obstructive pulmonary disease, furthermore, it is completely resistant to penicillin and to bacitracin. The natural hosts of Simkania negevensis bacteria might be amoebae.