Query: NC_008358:2808299 Hyphomonas neptunium ATCC 15444, complete genome Lineage: Hyphomonas neptunium; Hyphomonas; Hyphomonadaceae; Rhodobacterales; Proteobacteria; Bacteria General Information: Marine member of dimorphic prosthecate bacteria. This organism is also known as Hyphomicrobium neptunium. It has a biphasic life style, which consists of a motile phase of flagellated swarmer cells, and a cessile phase in which a long prosthecate is produced at one end of the bacteria through which budding cells emerge. Newly budded cells in turn produce flagella and go through a motile phase and the cycle continues. These organisms can colonize the surfaces of marine environments which enables additional species to colonize at later stages. This organism may be of use in treatment of water as they attach to a solid surface and are capable of degradation of a number of pollutants including aromatic hydrocarbons, dimethyl sulfoxide and methyl chloride.
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General Information: Etiologic agent of canine brucellosis. They are highly infectious, and can be spread through contact with infected animal products or through the air, making them a potential bioterrorism agent. Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Virulence may depend on a type IV secretion system which may promote intracellular growth by secreting important effector molecules. This bacterium is the causative agent of canine brucellosis. The main sources of infection are vaginal fluids of infected females and urine in males. The most significant symptoms are late abortions in bitches, epididymitis in males and infertility in both sexes, as well as generalized lymphadenitis, discospondylitis and uveitis. Human contagion is not frequent, although it has been reported, and is easily treated. B. canis can be differentiated from the other species of the genus Brucella (except B. ovis) in that it forms rugose colonies.