Query: NC_008343:2589680 Granulibacter bethesdensis CGDNIH1, complete genome Lineage: Granulibacter bethesdensis; Granulibacter; Acetobacteraceae; Rhodospirillales; Proteobacteria; Bacteria General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.
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Lineage: Caldicellulosiruptor obsidiansis; Caldicellulosiruptor; Thermoanaerobacterales Family III; Thermoanaerobacterales; Firmicutes; Bacteria
General Information: Country: USA; Environment: Hot spring; Habitat: Fresh water, Hot spring; Isolation: Obsidian Pool, Yellowstone National Park, USA; Temp: 55-85C. This species is an extremely thermophilic anaerobic bacteria, isolated from Obsidian Pool, Yellowstone National Park. It is a novel cellulolytic bacteria. Caldicellulosiruptor is a genus of thermophilic gram positive bacteria. These organisms produce a number of thermostable enzymes which may have industrial uses.