Query: NC_008343:2589680 Granulibacter bethesdensis CGDNIH1, complete genome Lineage: Granulibacter bethesdensis; Granulibacter; Acetobacteraceae; Rhodospirillales; Proteobacteria; Bacteria General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.
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General Information: This strain has been developed for worldwide commercial use to control crown gall. This species is used commercially to control crown gall, a tumorogenic plant disease caused by the ubiquitous soil-borne pathogen Agrobacterium tumefaciens, which affects susceptible woody plants worldwide. The pathogen is responsible for nursery and orchard losses among stone fruit trees, grapes, apples, pears, nut trees, caneberries, clematis, hops, kiwifruit, persimmons, roses and many ornamental annuals, trees and shrubs. Infected plants are usually weakened and unproductive due to their damaged root system.