Query: NC_008343:2589680 Granulibacter bethesdensis CGDNIH1, complete genome Lineage: Granulibacter bethesdensis; Granulibacter; Acetobacteraceae; Rhodospirillales; Proteobacteria; Bacteria General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.
- Sequence; - BLASTP hit: hover for score (Low score = Light, High score = Dark); - hypothetical protein; - cds: hover for description
General Information: Four different strains were isolated from 2 sites, one pristine and one polluted. Environmental bacterium with potential use in bioremediation. This organism has a diverse metabolism and is capable of growth using light, inorganic, or organic compounds as energy sources and carbon dioxide or organic compounds as carbon sources. Commonly found in soil and water environments this bacterium is also capable of degrading a wide range of toxic organic compounds, and may be of use in bioremediation of polluted sites. The bacterium undergoes differentiation to produce a stalked nonmotile cell and a motile flagellated cell. In the presence of light, this bacterium produces a number of intracellular membranous vesicles to house the photosynthetic reaction centers.