Query: NC_008343:1548020 Granulibacter bethesdensis CGDNIH1, complete genome Lineage: Granulibacter bethesdensis; Granulibacter; Acetobacteraceae; Rhodospirillales; Proteobacteria; Bacteria General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.
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General Information: The TC1 strain was isolated from a South Dakota, USA spill site soil that contained high concentrations (up to 29,000 microg/ml) of atrazine. Converts agricultural biomass to ethanol. Arthrobacter aurescens is found worldwide in the soil, water, and subsurface. It breaks down organic matter and is able to transform heavy metals into less toxic forms, such as the conversion of mercury salts into the neutral metal. It is also capable of utilizing t-anethole as a sole carbon source, and transforming it with high yield into valuable aromatic compounds which could potentially be used for aromas and flavorings.